Pneumothorax, Giant Bullae and Bronchiectasis in Pediatric Patients with a History of Pulmonary TB

Authors

  • Muzaijadah Retno Arimbi Universitas Wijaya Kusuma Surabaya, Indonesia
  • Lakcandra Amar Amori Universitas Airlangga Surabaya, Indonesia
  • Intan Nurani Indrajanu Universitas Airlangga Surabaya, Indonesia
  • Eka Nasrur Maulana Universitas Wijaya Kusuma Surabaya, Indonesia
  • Haryson Tondi Winoto Universitas Wijaya Kusuma Surabaya, Indonesia

DOI:

https://doi.org/10.46799/ijssr.v5i7.1278

Keywords:

pneumothorax, giant bullae, bronchiectasis, child, pulmonary tb

Abstract

Pulmonary tuberculosis (TB) remains a major infectious disease in children, particularly in developing countries. Post-TB pulmonary complications, such as pneumothorax, giant bullae, and bronchiectasis, can significantly impair respiratory function over time. This case report highlights a 17-year-old girl with a history of BTA-positive pulmonary TB who developed pneumothorax, giant bullae, varicose bronchiectasis, and centrilobular emphysema. After completing OAT therapy in August 2024, she underwent VATS, bulectomy, and wedge resection due to persistent lung abnormalities. Thoracic CT imaging revealed extensive lung damage, including bronchiectasis and bullae. Currently, the patient is stable and asymptomatic. This case emphasizes the importance of early detection and comprehensive management of post-TB bronchiectasis in pediatric patients. Timely intervention can improve prognosis, especially given the high regenerative capacity of children's lungs. Early recognition of complications and appropriate treatment are crucial to prevent long-term respiratory impairment in children recovering from pulmonary TB.

References

Ahmed, M. M., Ali, A. Y., & Hassan, M. S. (2017). Giant bullous disease: A review of diagnosis and management. Respiratory Medicine Case Reports, 22, 57–61. https://doi.org/10.1016/j.rmcr.2017.07.003

Alshammari, S. A., Alzahrani, A. K., & Aldosari, K. H. (2021). High-resolution computed tomography in diagnosing bronchiectasis in children with persistent cough. Journal of Pediatric Pulmonology, 56(2), 411–418. https://doi.org/10.1002/ppul.25160

Bhalla, M., Turcios, N., & Aponte, V. (2015). High-resolution CT of bronchiectasis: Current perspectives. Clinical Radiology, 70(7), 722–733. https://doi.org/10.1016/j.crad.2015.03.015

Hariyanto W., & Hasan H. (2016). Bronchiectasis. Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga.

Kuo, Y. W., Ciet, P., Tiddens, H., & De Jong, P. A. (2018). Imaging of bronchiectasis: Current perspectives. Clinical Imaging, 52, 1–10. https://doi.org/10.1016/j.clinimag.2018.05.006

Lanzafame, M., & Vento, S. (2016). Tuberculosis-immune reconstitution inflammatory syndrome. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 3, 6-9.

Lee, K. H., Yoon, H. K., & Lee, J. H. (2019). Spontaneous pneumothorax associated with bullous lung disease. Korean Journal of Thoracic Disease, 11(1), 53–61. https://doi.org/10.21037/jtd.2019.01.11

Ministry of Health. (2020). National guidelines for medical services for tuberculosis management. Jakarta.

Ministry of Health. (2016). Technical Instructions for Childhood TB Management and Management. Jakarta.

Ministry of Health. (2023). Technical guidelines for the management of tuberculosis in children and adolescents. Jakarta: Ministry of Health of the Republic of Indonesia.

Marhana, I. A., Amin, M., Permatasari, A., & Rosyid, A. N. (Eds.). (2022). Pulmonary Textbook 2022. Airlangga University Press.

Mohamed, A. A., Ibrahim, M. T., & Khalifa, H. A. (2023). Multidetector CT evaluation of pediatric bronchiectasis: Patterns and associations. Egyptian Journal of Radiology and Nuclear Medicine, 54(1), 12. https://doi.org/10.1186/s43055-023-01102-7

Park, S. Y., Kim, Y. H., & Jeon, H. W. (2020). Giant bullae of the lung: Imaging findings and surgical management. Journal of Thoracic Imaging, 35(3), W59–W64. https://doi.org/10.1097/RTI.0000000000000447

Pawlowski, A., Jansson, M., Sköld, M., Rottenberg, M. E., & Källenius, G. (2012). Tuberculosis and HIV co-infection. PLoS pathogens, 8(2), e1002464.

Safarudin, R., Zulfamanna, Z., Kustati, M., & Sepriyanti, N. (2023). Qualitative research. Innovative: Journal Of Social Science Research, 3(2), 9680-9694.

Shah, I., & Bhaskar, M. V. (2017). Paradoxical reactions in children with tuberculosis. Tropical Doctor, 47(2), 109-113.

Simanjuntak, D. R. O., Pantow, S. G. I., Darto, S., & Dewiyanti, L. (2023). A Patient With Ruptured Bullae Caused By Intrapulmonary Complications Of Tuberculosis: A Case Report. Health Information: Journal of Research.

Tran, H. D., Pham, Q. H., & Le, V. H. (2020). Diagnostic value of HRCT in detecting bronchiectasis in pediatric patients. Journal of Clinical Imaging Science, 10(1), 8. https://doi.org/10.25259/JCIS_20_2020

Tschopp, J. M., Bintcliffe, O., Astoul, P., & Janssen, J. (2015). Management of spontaneous pneumothorax: State of the art. European Respiratory Review, 24(136), 442–450. https://doi.org/10.1183/16000617.00001015

Yumma, M. & Mayasari, H.N. (2022). A Man with Bronchiectasis and History of Tuberculosis.

Yoo, J. W., Kim, H. C., & Ryu, Y. J. (2016). Pulmonary complications of bullae: Clinical perspectives. Tuberculosis and Respiratory Diseases, 79(2), 81–88. https://doi.org/10.4046/trd.2016.79.2.81

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Published

2025-07-18